Effect of Graded Levels of Lipton Tea Extract on Haematological Parameter in Albino Wistar Rat (Rattus norvegicus)


Leelee Famii Zitte and James Kelechi Onyekwere


This study investigates the effects of graded levels of Lipton tea extract on the
Haematological parameters in white albino rats (Rattus norvegicus). A total of 20 white
albino rats weighing 120-160g, were divided into five (5) groups (I, II, III, IV, and V) of
four rats per group. Doses of 50mg/kg/day, 250mg/kg/day, 500mg/kg/per, and
1000mg/kg/day of Lipton tea extract were orally administered for three weeks to
treatment groups (II, III, IV, and V), while rats in group I were given only water and
served as control. Blood samples were collected from the sacrificial animals to
determine the effect of Lipton tea extract on haematological parameters (RBC, WBC, PCV,
Hb, and platelet), liver enzymes (AST and ALT) & lipid profile (HDL, LDL, TG, and TC).
The haematological analysis showed a significant difference (P<0.05) in WBC, but no
significant difference (P>0.05) in the levels of RBC, PCV, Hb, and platelet compared to
the control. Serum levels of AST and ALT showed significant difference (P<0.05) across
the groups from the control. The lipid profile test showed no significant difference
(P>0.05) in HDL, LDL, and TC from the control while TG was significantly different
(P<0.05) from the control. The result of the study showed that Lipton tea has no
negative effect in the blood.
Keywords: Rattus norvegicus, Lipton tea, Haematological parameters and liver enzymes





Leelee Famii Zitte and James Kelechi Onyekwere (2023). Effect of Graded Levels of Lipton Tea Extract on HaematologicalParameter in Albino Wistar Rat (Rattus norvegicus). IAA Journal of Biological Sciences, 10(1):164-167.