Future Directions in Cancer Genomics Research and Capacity Building in East Africa
Masika Anna Mahinda
Department of Pharmacy Kampala International University Uganda
Email: mahindamasika@studwc.kiu.ac.ug
ABSTRACT
Cancer genomics has transformed cancer diagnosis, treatment, and precision medicine globally, yet East Africa remains underrepresented in these advancements. This review examines the current landscape of cancer genomics research and capacity in East African countries, highlighting critical gaps in laboratory infrastructure, trained personnel, data systems, ethical and regulatory frameworks, and sustainable financing. Key challenges include fragmented research efforts, reliance on short-term donor funding, limited integration of genomics into national cancer control strategies, and inequitable access to innovations. The review proposes strategic directions for building a robust and sustainable genomics ecosystem, including networked sequencing hubs, human capital development through targeted training and career pathways, standardized cancer registries, ethical governance, blended financing models, and regional collaboration through consortia and Centers of Excellence. Addressing risks such as brain drain, donor dependence, and data privacy is emphasized to ensure equity and long-term sustainability. Implementing these strategies can enable precision oncology, generate locally relevant data, and improve cancer outcomes across East Africa.
Keywords: Cancer genomics, East Africa, precision medicine, capacity building, infrastructure, human resources.
CITE AS: Masika Anna Mahinda (2026). Future Directions in Cancer Genomics Research and Capacity Building in East Africa. IAA Journal of Biological Sciences 14(1):8-11.