In recent times, the use of many medicinal plants for healing purposes has been abused. Turmeric is
one of the medicinal plants used indiscriminately for different purposes in ethnomedicine, without
adequate attention to any apparent adverse effect such use may pose to the health status of the
individual. This study was carried out to assess the hepatic and renal biochemical profile of powdered
turmeric supplement (PTS)-fed-wistar rats. A total of twenty male animals were randomly assigned to
4 groups, 5 per group. Group A (Control) = 1ml of distilled water, Group B = 250mg/kg PTS, Group C =
500 mg/kg PTS and Group D = 1000 mg/kg PTS. All administrations were by oral gavage daily for 28
days. At the end of the administrations, blood samples were collected for the estimation of serum
concentrations of Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), Alkaline
Phosphatase (ALP), Total Protein (TP), Albumin (ALB), Creatinine and Urea. PTS caused a significant
(p<0.05) decrease in serum AST in comparison with the control. There was no significant (p> 0.05)
effect in the serum ALP, ALT, TP, ALB, Creatinine and Urea concentrations relative to the control. It was
therefore concluded that under the conditions of this study, powdered turmeric supplement had no
toxic effect on serum hepatic and renal biochemical parameters.
Keywords: Hepatic, Renal, Biochemical Profile, Turmeric and Supplement

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